The right dosage for TB-500

For all of time prior to the Internet, men could rely on only their own trial and error and conversations with friends to ascertain what behaviors produced success with women. Suddenly, in the 21st century, men from all over the world could compare experiences. Like an early form of AI, they were able to make accurate predictions based on data from a sample size of millions.

Something similar is happening in the health sphere. Big Medicine has no interest in funding expensive trials that would validate biohackers’ cheap and effective treatments. Nevertheless, legions of red meat-enjoying, vaccine-avoiding, raw milk-drinking, carbohydrate-restricting and sunlight-receiving individuals are comparing experiences. They are able to make accurate predictions based on data from a sample size that is growing into millions.    

One area where the data is piling up is the use of peptides to heal injuries. I myself have tried BPC-157. Although the heal-like-a-superhero hype is exaggerated, you do wake up one day after a month of injections and realize your pain is gone.

BPC-157 works by causing your body to make more of the protein actin, which plays a central role in cell reproduction. To your cycle of BPC-157, you can also add a series of the peptide TB-500, which helps your body circulate actin more efficiently. I am trying this powerful combination now for my stubborn plantar fasciitis.

The most significant problem with peptides is the do-it-yourself prep of the recommended doses. With a calculator or even a peptide calculator webpage, there are too many variables for the mathematically challenged. The administration of peptides starts with: some quantity of dried peptide (measured in milligrams) in a small vial; reconstitution solution (measured in milliliters) in a large vial; and the daily or bi-weekly injected dose (measured in micrograms or milligrams) that goes into a 1ml insulin syringe.

If you explore the Internet to learn about dosing of BPC-157, one of the first search results is a detailed article from a health and wellness podcaster. He wrote, “The first time I used it, I accidentally dosed with 2500mcg instead of the 250mcg I planned to initially trial with. I felt for about the next four hours what I would best describe as a slight amount of irritability and grumpiness.”

I’m a pro with the dosing of BPC-157, but the TB-500 blew my mind. TB-500 comes from the manufacturer in a 5mg quantity, and I wanted to reconstitute it so I would get two 2mg doses per week out of the vial. Due to my faulty calculations, I tried to completely fill the TB-500 vial with reconstitution solution. I ended up wasting several insulin syringes and having embarrassing amounts of bacteriostatic water run down the side of the vial. I also inadvertently squirted solution all over my desk and computer monitor when I tried to expedite the reconstitution process with a 10ml science lab syringe. The mess I made proved irrelevant, however. My next move was to accidentally knock the vial off my desk and send it bouncing along my tile floor. The fragile peptides inside were rendered useless.

The good news is that as I spent time thinking about this incident, I came up with the right equation for the next 5mg vial. It’s simply: 1.5ml of bacteriostatic water diluting 5mg of peptide, which yields 2mg of TB-500 with the insulin syringe pulled to 60 units.

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